NEW PROCEDURAL NOTICES OF THE CZECH OFFICE FOR THE PROTECTION OF COMPETITION: LENIENCY, SETTLEMENT, AND ALTERNATIVE PROBLEM RESOLUTION

New Procedural Notices of the Czech Office for the Protection of Competition: Leniency, Settlement, and Alternative Problem Resolution

In connection with the 2012 amendment of the Czech Act on the Protection of Competition (hereafter, APC), reported in YARS last year1, the Czech Office for the Protection of Competition (hereafter, Office) issued three new procedural Greens noticesin November 2013: Notice of the Office for the Protection of Competition of 4 November 2013 on the app

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Core Proteomics and Immunoinformatic Approaches to Design a Multiepitope Reverse Vaccine Candidate against Chagas Disease

Chagas disease is a tropical ailment indigenous to South America and caused by the protozoan parasite Trypanosoma cruzi, which has serious health consequences globally.Insect vectors transmit the parasite and, due to the lack of vaccine availability and limited treatment options, we implemented an integrated core proteomics analysis to design a rev

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Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis.

Dimethyl fumarate (DMF) suede-chinks-with-basketweave-accents is a first-line prodrug for the treatment of relapsing-remitting multiple sclerosis (RRMS) that is completely metabolized to monomethyl fumarate (MMF), the active metabolite, before reaching the systemic circulation.Its metabolism has been proposed to be due to ubiquitous esterases in th

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